Description

Boc-5-Aminopyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in the construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl systems.
• Material Science: Employed in the synthesis of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a tool compound or linker in the development of chemical probes and affinity purification reagents.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	Boc-5-Aminopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310404-08-0
Molecular Formula	C₁₇H₂₇BN₂O₄
Molecular Weight	334.22 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]pyridine-2-boronic acid pinacol ester; 2-Borono-5-[(tert-butoxycarbonyl)amino]pyridine pinacol ester; tert-Butyl (6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate; Boc-5-Amino-2-pyridylboronic acid pinacol ester; 5-(Boc-amino)-2-pyridylboronic acid pinacol ester; N-Boc-5-amino-2-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Boc-5-Aminopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.