Description

6-Ethoxypyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl or vinyl halides to form biaryl or styrenyl structures, a cornerstone of drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and coordination chemistry.
• Material Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology and Probe Development: Acts as a handle for bioconjugation or in the synthesis of molecular probes for biological target identification.

Basic Information

Product Name	6-Ethoxypyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310385-03-5
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	2-(6-Ethoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Ethoxy-2-pyridineboronic acid pinacol ester; 2-(6-Ethoxy-2-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Ethoxypyridine-2-boronic acid neopentyl glycol ester (common alternative); 2-(6-Ethoxypyridin-2-yl)-1,3,2-dioxaborinane (if cyclic ester); B-(6-Ethoxypyridin-2-yl)boronic acid pinacol ester; 6-Ethoxy-2-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Ethoxypyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.