Description

6-(3-Oxopropanoyl)Pyridine-3-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid and a reactive keto-acid group, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Suzuki-Miyaura Cross-Coupling: Essential boronic acid partner for palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl bonds, a cornerstone of modern drug discovery.
• Medicinal Chemistry & Library Synthesis: Used to introduce the pyridine-boronic acid pharmacophore and for the rapid parallel synthesis of compound libraries for high-throughput screening.
• Agrochemical Research: Employed in the development of novel herbicides and insecticides, leveraging its heterocyclic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein interactions.

Basic Information

Product Name	6-(3-Oxopropanoyl)Pyridine-3-Boronic Acid
CAS No.	1310384-29-2
Molecular Formula	C9H8BNO4
Molecular Weight	205.98 g/mol
Synonyms	3-Pyridineboronic acid, 6-(3-oxo-1-oxopropyl)-; 6-(3-Oxopropanoyl)-3-pyridineboronic acid; (6-(3-Oxopropanoyl)pyridin-3-yl)boronic acid; 3-Borono-6-(3-oxopropanoyl)pyridine; 5-Borono-2-(3-oxopropanoyl)pyridine; 6-(3-Oxopropionyl)pyridine-3-boronic acid; 1310384-29-2; AKOS026710793
EINECS	Contact for details

Quality Control

Every batch of 6-(3-Oxopropanoyl)Pyridine-3-Boronic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.