Description

2-tert-Butyloxycarbonylamino-5-Nitropyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for coupling reactions, such as Suzuki-Miyaura cross-couplings, to construct complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing functionalized pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a boronic ester coupling partner for the formation of carbon-carbon bonds in complex molecule assembly.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.
• Material Science: Building block for creating organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	2-tert-Butyloxycarbonylamino-5-Nitropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309982-63-5
Molecular Formula	C16H24BN3O6
Molecular Weight	365.19 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-5-nitropyridine-3-boronic acid pinacol ester; 2-(Boc-amino)-5-nitro-3-pyridineboronic acid pinacol ester; 5-Nitro-2-((tert-butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; 3-Borono-5-nitro-2-pyridinamine, N-Boc-, pinacol ester; Boc-Protected 5-Nitro-3-pyridinylboronic Acid Pinacol Ester; 1309982-63-5; (2-((tert-Butoxycarbonyl)amino)-5-nitropyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-tert-Butyloxycarbonylamino-5-Nitropyridine-3-Boronic Acid Pinacol Ester is analyzed using advanced techniques including HPLC, NMR, and LC-MS to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.