Description

6-(2-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. This compound matters because it enables efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex heterocyclic systems.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming biaryl and other carbon-carbon bonds in the presence of palladium catalysts under mild conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic motifs.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Process Chemistry & Scale-up: Utilized in route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	6-(2-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309982-28-2
Molecular Formula	C17H27BN2O2
Molecular Weight	302.22 g/mol
Synonyms	2-(6-(2-Methylpiperidin-1-yl)pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-(2-Methyl-1-piperidinyl)-2-pyridineboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[6-(2-methyl-1-piperidinyl)-2-pyridinyl]-4,4,5,5-tetramethyl-; 6-(2-Methylpiperidino)pyridine-2-boronic acid pinacol ester; 2-(6-(2-Methylpiperidin-1-yl)pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[6-(2-methyl-1-piperidinyl)-2-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(2-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.