Description

5-Amino-6-Ethoxypyridine-3-Boronic Acid is a high-value, multifunctional heterocyclic building block essential for modern synthetic chemistry. This compound matters because its unique structure combines a protected amino group, an ethoxy substituent, and a versatile boronic acid moiety, making it a critical intermediate for constructing complex molecules via cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive boronic acid handle.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and catalysis studies within university and CRO laboratories.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals and complex organic molecules for various high-tech applications.

Basic Information

Product Name	5-Amino-6-Ethoxypyridine-3-Boronic Acid
CAS No.	1309982-25-9
Molecular Formula	C7H11BN2O3
Molecular Weight	182.0 g/mol
Synonyms	(5-Amino-6-ethoxy-3-pyridinyl)boronic acid; 5-Amino-6-ethoxy-3-pyridineboronic acid; 3-Borono-5-amino-6-ethoxypyridine; 6-Ethoxy-5-aminopyridine-3-boronic acid; 5-Amino-6-ethoxypyridin-3-ylboronic acid; Boronic acid, B-(5-amino-6-ethoxy-3-pyridinyl)-; 1309982-25-9
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Ethoxypyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.