Description

Isopropyl 2-Hydroxy-3,3,3-Trifluoro-2-(Trifluoromethyl)Propionate is a specialized fluorinated ester building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, featuring a highly fluorinated hydroxypropionate core, which imparts valuable properties like enhanced lipophilicity and metabolic stability to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of advanced materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl-hydroxypropionate moiety into potential drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorinated segment can improve bioavailability and environmental persistence profiles.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the synthesis of fluorinated polymers and coatings, contributing to properties like oil/water repellency, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the development of fluorinated components for liquid crystal displays (LCDs) and other electronic materials due to its polar and stable chemical structure.
• Fine Chemical Building Block: Utilized in custom synthesis and contract manufacturing for producing complex, high-value fluorinated compounds for various research and industrial applications.

Basic Information

Product Name	Isopropyl 2-Hydroxy-3,3,3-Trifluoro-2-(Trifluoromethyl)Propionate
CAS No.	1309602-08-1
Molecular Formula	C8H10F6O3
Molecular Weight	268.16 g/mol
Synonyms	2-Hydroxy-3,3,3-trifluoro-2-(trifluoromethyl)propionic acid isopropyl ester; Isopropyl 2-hydroxy-3,3,3-trifluoro-2-(trifluoromethyl)propanoate; 1-Methylethyl 2-hydroxy-3,3,3-trifluoro-2-(trifluoromethyl)propionate; α-Hydroxy-α-(trifluoromethyl)-β,β,β-trifluoropropionic acid isopropyl ester; TFHP-IP ester; Fluorinated hydroxypropionate ester
EINECS	Contact for details

Quality Control

Our Isopropyl 2-Hydroxy-3,3,3-Trifluoro-2-(Trifluoromethyl)Propionate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC/NMR), impurity profiles, and physical characteristics are provided and available upon request. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, or at controlled room temperature for short-term use. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.