Description

Benzyl-Peg2-Ch2Co2Tbu CAS NO 1309451-06-6 is a specialized bifunctional PEG derivative featuring a benzyl-protected aromatic group and a tert-butyl ester terminus. This compound is a crucial intermediate in the synthesis of complex molecules, offering controlled conjugation and solubility enhancement. It is primarily utilized by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing targeted drug delivery systems, antibody-drug conjugates (ADCs), and advanced polymer materials.

Application

• Key intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Functional linker for PEGylation of peptides, proteins, and small molecule drugs to improve pharmacokinetics.
• Building block for constructing dendrimers and advanced, multi-arm polymer scaffolds.
• Used in the development of prodrugs where the tert-butyl ester provides a cleavable protecting group.
• Essential reagent in bioconjugation chemistry and materials science for surface functionalization.
• Research chemical for exploring novel drug delivery platforms and solubility enhancement strategies.

Basic Information

Product Name	Benzyl-Peg2-Ch2Co2Tbu
CAS No.	1309451-06-6
Molecular Formula	C19H30O6
Molecular Weight	354.44 g/mol
Synonyms	1-Benzyl-3,6,9,12-tetraoxapentadecan-15-oic acid tert-butyl ester; 2-[2-(2-Benzyloxyethoxy)ethoxy]acetic acid tert-butyl ester; tert-Butyl 2-[2-(2-benzyloxyethoxy)ethoxy]acetate; Benzyl-PEG2-CH2COOtBu; Bn-PEG2-CH2COOtBu; Benzyl-PEG2-acetic acid t-butyl ester; Benzyl tetraethylene glycol acetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Benzyl-Peg2-Ch2Co2Tbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.