Description

Ethyl 2-(4-Acetylphenyl)-2,2-Difluoroacetate is a high-purity fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of difluoroacetate and acetylphenyl motifs is critical. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting metabolic and central nervous system disorders.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where the difluoroacetate group can enhance biological activity and stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis: Employed in cross-coupling reactions and as a substrate for further functionalization to create complex fluorinated aromatic compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethyl 2-(4-Acetylphenyl)-2,2-Difluoroacetate
CAS No.	1308915-15-2
Molecular Formula	C₁₂H₁₂F₂O₃
Molecular Weight	242.22 g/mol
Synonyms	Ethyl 4-Acetyl-α,α-difluorophenylacetate; 2-(4-Acetylphenyl)-2,2-difluoroacetic Acid Ethyl Ester; 4-Acetyl-α,α-difluorobenzeneacetic Acid Ethyl Ester; Ethyl (4-Acetylphenyl)difluoroacetate; Difluoro(4-acetylphenyl)acetic Acid Ethyl Ester; Ethyl 2,2-Difluoro-2-(4-acetylphenyl)acetate; 1308915-15-2; 4-Acetyl-α,α-difluorophenylacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Acetylphenyl)-2,2-Difluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.