Description

Ethyl 3-(2-Cyano-n-Methylacetamido)Propanoate is a specialized cyanoacetamide derivative ester, serving as a crucial high-purity building block in advanced organic synthesis. Its molecular structure, featuring both cyano and ester functional groups, makes it a versatile intermediate for constructing complex heterocycles and active pharmaceutical ingredients (APIs). This compound is primarily sought by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and insecticides, leveraging its reactive cyanoacetamide moiety.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific molecular architectures.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Peptidomimetic Research: The structure is conducive to the development of peptide analogs and enzyme inhibitors.

Basic Information

Product Name	Ethyl 3-(2-Cyano-n-Methylacetamido)Propanoate
CAS No.	1306948-45-7
Molecular Formula	C9H14N2O3
Molecular Weight	198.22 g/mol
Synonyms	Ethyl 3-[(2-cyanoacetyl)(methyl)amino]propanoate; 3-[(2-Cyanoacetyl)(methyl)amino]propanoic acid ethyl ester; Ethyl 3-((2-cyanoacetyl)(methyl)amino)propanoate; N-Methyl-N-(3-ethoxy-3-oxopropyl)-2-cyanoacetamide; Propanoic acid, 3-[(2-cyanoacetyl)(methyl)amino]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2-Cyano-n-Methylacetamido)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with your research and production standards. Custom purity grades, including >98% and >99%, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.