Description

Methyl 3-Bromo-5-(Trifluoromethoxy)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the electronic properties and lipophilicity of target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Functional Material Development: Used in the synthesis of specialty polymers, ligands for catalysis, and other advanced functional materials requiring specific aromatic frameworks.

Basic Information

Product Name	Methyl 3-Bromo-5-(Trifluoromethoxy)Benzoate
CAS No.	1306763-53-0
Molecular Formula	C9H6BrF3O3
Molecular Weight	299.04 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzoic acid methyl ester; Methyl 3-bromo-5-(trifluoromethoxy)benzoate; Benzoic acid, 3-bromo-5-(trifluoromethoxy)-, methyl ester; Methyl 3-bromo-α,α,α-trifluoro-m-anisate; 3-Bromo-5-trifluoromethoxybenzoic Acid Methyl Ester; Methyl 3-Bromo-5-(trifluoromethoxy)benzenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.