Description

tert-Butyl (9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undec-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and carbamate-protected amine structure. This compound is critical for enabling sophisticated synthetic routes in modern drug discovery and development, offering a protected functional handle for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for constructing complex molecular architectures in drug candidates.
• Protease Inhibitor Research: Used in the development of novel inhibitors targeting specific enzymatic pathways.
• CNS-Active Compound Development: Applied in the research and synthesis of potential therapeutics for neurological disorders.
• Peptidomimetic Chemistry: Functions as a scaffold in the design of peptide-like molecules with enhanced stability and bioavailability.
• Medicinal Chemistry & Lead Optimization: Provides a versatile intermediate for structure-activity relationship (SAR) studies during lead compound optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.

Basic Information

Item	Detail
Product Name	tert-Butyl (9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undec-4-Yl)Carbamate
CAS No.	1306739-43-4
Molecular Formula	C21H31NO3
Molecular Weight	345.48 g/mol
Synonyms	Boc-9-Benzyl-1-oxa-9-azaspiro[5.5]undecan-4-amine; N-Boc-9-Benzyl-1-oxa-9-azaspiro[5.5]undecan-4-amine; tert-Butyl N-(9-benzyl-1-oxa-9-azaspiro[5.5]undec-4-yl)carbamate; 9-Benzyl-1-oxa-9-azaspiro[5.5]undec-4-amine, N-[(1,1-dimethylethoxy)carbonyl]-; 1306739-43-4; (9-Benzyl-1-oxa-9-azaspiro[5.5]undec-4-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (9-Benzyl-1-Oxa-9-Azaspiro[5.5]Undec-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.