Description

1-tert-Butyl 4-Methyl 4-Propylpiperidine-1,4-Dicarboxylate is a high-purity, synthetic organic compound belonging to the piperidine dicarboxylate ester class, serving as a crucial advanced pharmaceutical intermediate and a versatile building block in fine chemical synthesis. Its defined stereochemistry and functional groups make it an essential precursor for the development of complex active pharmaceutical ingredients (APIs) and novel chemical entities. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and therapeutic agent research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Process Chemistry Development: Serves as a standardized intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Synthesis: Employed in the preparation of specialty chemicals, ligands, and catalysts requiring specific piperidine-based architectures.
• Academic Research: Utilized in universities and R&D labs for methodological studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client programs.

Basic Information

Product Name	1-tert-Butyl 4-Methyl 4-Propylpiperidine-1,4-Dicarboxylate
CAS No.	1306738-94-2
Molecular Formula	C15H27NO4
Molecular Weight	285.38 g/mol
Synonyms	4-Propyl-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-methyl ester; 1-(tert-Butyl) 4-methyl 4-propylpiperidine-1,4-dicarboxylate; 4-Propylpiperidine-1,4-dicarboxylic acid 1-tert-butyl 4-methyl ester; tert-Butyl methyl 4-propylpiperidine-1,4-dicarboxylate; 1-Boc-4-methyl 4-propylpiperidine-1,4-dicarboxylate; 4-Propyl-1-Boc-piperidine-4-carboxylic acid methyl ester; CAS 1306738-94-2
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl 4-Propylpiperidine-1,4-Dicarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided and available upon request. We support development and commercial projects with material that meets the stringent requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.