Description

[1-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Pyrrolidin-2-Yl]-Methanol is a high-value, multi-functional heterocyclic building block featuring a unique pyridine-pyrrolidine scaffold with chloro and trifluoromethyl substituents. This compound matters for its critical role as a versatile intermediate in modern synthetic chemistry, enabling the development of novel molecules with tailored properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	[1-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Pyrrolidin-2-Yl]-Methanol
CAS No.	1306120-26-2
Molecular Formula	C11H10ClF3N2O
Molecular Weight	278.66 g/mol
Synonyms	(2-Pyrrolidinyl)methanol, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrrolidin-2-ylmethanol; 2-Pyrrolidinemethanol, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-2-ylmethanol; (1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our [1-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Yl)-Pyrrolidin-2-Yl]-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.