Description

tert-Butyl 3-Bromo-5-Iodo-1H-Pyrazolo-[3,4-B]Pyridine-1-Carboxylate is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in kinase inhibitor research. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for targeted therapies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of small molecule kinase inhibitors and other biologically active compounds.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and cellular pathways.
• Agrochemical Synthesis: Potential intermediate in the research and development of new active ingredients for crop protection.
• Material Science: Can be utilized in the synthesis of complex organic molecules for advanced materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services.

Basic Information

Product Name	tert-Butyl 3-Bromo-5-Iodo-1H-Pyrazolo-[3,4-B]Pyridine-1-Carboxylate
CAS No.	1305325-03-4
Molecular Formula	C11H9BrIN3O2
Molecular Weight	421.02 g/mol
Synonyms	1-Boc-3-bromo-5-iodo-1H-pyrazolo[3,4-b]pyridine; tert-Butyl 3-bromo-5-iodo-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 3-Bromo-5-iodo-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 3-bromo-5-iodo-, 1,1-dimethylethyl ester; 3-Bromo-5-iodo-1-(tert-butoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine; Boc-3-Bromo-5-Iodo-pyrazolopyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-5-Iodo-1H-Pyrazolo-[3,4-B]Pyridine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-grade standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.