Description

3,4-Diiodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated structure. This compound is essential for advanced research and development, particularly in the synthesis of novel, complex molecules. It is primarily sought after by pharmaceutical and agrochemical R&D teams for creating targeted active ingredients and by material scientists exploring new functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the bioactivity of the pyrrolopyridine core and halogen substituents.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry for studying biological processes.
• Cross-Coupling Reactions: The iodine atoms make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3,4-Diiodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1305324-86-0
Molecular Formula	C8H3F3I2N2
Molecular Weight	461.93 g/mol
Synonyms	5-(Trifluoromethyl)-3,4-diiodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3,4-diiodo-5-(trifluoromethyl)-; 3,4-Diiodo-5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 3,4-Diiodo-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1305324-86-0; 5-Trifluoromethyl-3,4-diiodo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3,4-Diiodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.