Description

5-Chloro-2,3-Dimethoxyisonicotinic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Advanced Material Development: A building block for organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	5-Chloro-2,3-Dimethoxyisonicotinic Acid
CAS No.	1305324-74-6
Molecular Formula	C8H8ClNO4
Molecular Weight	217.61 g/mol
Synonyms	5-Chloro-2,3-dimethoxypyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-chloro-2,3-dimethoxy-; 5-Chloro-2,3-dimethoxy-4-pyridinecarboxylic acid; 5-Chloro-2,3-dimethoxyisonicotinate; 1305324-74-6; 5-Cl-2,3-(OMe)2-isonicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Dimethoxyisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.