Description

7-Chloro-8-(Trimethylsilyl)-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is a high-value, organosilicon-functionalized heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its unique structural features, combining a halogenated dioxinopyridine core with a reactive trimethylsilyl group, enabling precise molecular construction. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by material scientists developing specialty chemicals and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in constructing novel pesticides and herbicides, leveraging its halogenated heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a building block for creating specialty polymers, ligands, and silicon-containing advanced materials.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, functional group transformations, and as a protecting group strategy in complex multi-step syntheses.
• Chemical Research: Employed in academic and industrial laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	7-Chloro-8-(Trimethylsilyl)-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine
CAS No.	1305324-58-6
Molecular Formula	C12H16ClNO2Si
Molecular Weight	269.80 g/mol
Synonyms	7-Chloro-8-(trimethylsilyl)-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 2,3-Dihydro-7-chloro-8-(trimethylsilyl)-1,4-dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridine, 7-chloro-8-(trimethylsilyl)-2,3-dihydro-; 1305324-58-6; TMS-Dioxinopyridine derivative; Chloro(trimethylsilyl)dioxinopyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-(Trimethylsilyl)-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for critical R&D and scale-up applications. Certificates of Analysis (COA) with full specification data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.