Description

1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and piperidine sulfonamide scaffold. This compound matters as a critical building block for medicinal chemists developing novel small-molecule therapeutics, particularly kinase inhibitors and other targeted agents. It is essential for research and development laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Key synthetic intermediate in the research and development of kinase inhibitors for oncology and inflammatory diseases.
• Building block for constructing sulfonamide-based bioactive molecules in medicinal chemistry programs.
• Precursor in the synthesis of targeted protein degraders (PROTACs) leveraging its heterocyclic structure for linker design.
• Used in process development and scale-up for Active Pharmaceutical Ingredient (API) manufacturing.
• Valuable scaffold in high-throughput screening libraries for identifying new lead compounds.
• Intermediate for agrochemical research, exploring new fungicides or herbicides.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-3-Amine
CAS No.	1305209-21-5
Molecular Formula	C10H14BrN3O2S
Molecular Weight	320.21 g/mol
Synonyms	3-Amino-1-(5-bromopyridine-3-sulfonyl)piperidine; 1-[(5-Bromo-3-pyridinyl)sulfonyl]-3-piperidinamine; 3-Piperidinamine, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1-(5-Bromo-3-pyridinesulfonyl)piperidin-3-amine; 1305209-21-5; 5-Bromo-3-(3-aminopiperidine-1-sulfonyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.