Description

2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Quinoline] is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and quinoline-based molecular architecture. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel drug candidates, particularly those targeting central nervous system and oncological pathways. It is primarily sought after by R&D laboratories, custom synthesis providers, and pharmaceutical companies engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in drug discovery programs.
• Organic Synthesis: Employed in academic and industrial research for studying spirocyclic and heterocyclic reaction mechanisms.
• API Development: Serves as a critical intermediate in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized in the design of molecular probes for investigating biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Quinoline]
CAS No.	1304598-29-5
Molecular Formula	C12H13N
Molecular Weight	171.24 g/mol
Synonyms	1'H-Spiro[cyclopropane-1,4'-quinoline], 2',3'-Dihydro-; Spiro[cyclopropane-1,4'-quinoline], 2',3'-dihydro-1'H-; 1'H-Spiro(cyclopropane-1,4'-quinoline), 2',3'-dihydro-; 2,3-Dihydro-1H-spiro[cyclopropane-1,4'-quinoline]; 1304598-29-5
EINECS	Contact for details

Quality Control

Every batch of 2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Quinoline] is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency of the material meet the exacting standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.