Description

5-Bromo-n-(1-Methylpyrrolidin-3-Yl)Pyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1304557-79-6. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Bioconjugation & Probe Development: The sulfonamide and bromo functional groups make it suitable for creating chemical probes for biochemical assays and diagnostic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	5-Bromo-n-(1-Methylpyrrolidin-3-Yl)Pyridine-3-Sulfonamide
CAS No.	1304557-79-6
Molecular Formula	C11H14BrN3O2S
Molecular Weight	332.22 g/mol
Synonyms	5-Bromo-N-(1-methyl-3-pyrrolidinyl)-3-pyridinesulfonamide; 3-Pyridinesulfonamide, 5-bromo-N-(1-methyl-3-pyrrolidinyl)-; 5-Bromo-N-(1-methylpyrrolidin-3-yl)pyridine-3-sulfonamide; 1304557-79-6; 5-Br-N-(1-Me-pyrrolidin-3-yl)-pyridine-3-sulfonamide; BMS Intermediate; Sulfonamide Pyrrolidine Pyridine Bromo Derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(1-Methylpyrrolidin-3-Yl)Pyridine-3-Sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced intermediates and can tailor quality documentation to meet specific client and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.