Description

[4-(Piperidin-1-Ylmethyl)Phenyl]Boronic Acid Hydrochloride is a high-purity, synthetically valuable boronic acid derivative, primarily used as a key building block in modern organic synthesis. Its core value proposition lies in enabling the formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile organoboron reagent for palladium-catalyzed cross-coupling to create biaryl and heterobiaryl structures, which are common pharmacophores.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Acts as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and affinity ligands for studying biological systems.

Basic Information

Product Name	[4-(Piperidin-1-Ylmethyl)Phenyl]Boronic Acid Hydrochloride
CAS No.	1301198-10-6
Molecular Formula	C13H21BClNO2
Molecular Weight	269.57 g/mol
Synonyms	4-(Piperidin-1-ylmethyl)benzeneboronic acid hydrochloride; (4-((Piperidin-1-yl)methyl)phenyl)boronic acid hydrochloride; 1-[4-(Boronophenyl)methyl]piperidine hydrochloride; B-[4-(1-Piperidinylmethyl)phenyl]boronic acid hydrochloride; 4-(Piperidin-1-ylmethyl)phenylboronic acid HCl; 1301198-10-6; Boronic acid, B-[4-(1-piperidinylmethyl)phenyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our [4-(Piperidin-1-Ylmethyl)Phenyl]Boronic Acid Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with the standards expected in pharmaceutical development, ensuring reliable performance in sensitive cross-coupling reactions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.