Description

3-Chloro-5-Iodopyridin-4-Amine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	3-Chloro-5-Iodopyridin-4-Amine
CAS No.	1300750-79-1
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	4-Amino-3-chloro-5-iodopyridine; 3-Chloro-5-iodopyridin-4-ylamine; 5-Iodo-3-chloropyridin-4-amine; 3-Chloro-5-iodo-4-pyridinamine; 4-Pyridinamine, 3-chloro-5-iodo-; 3-Chloro-5-iodo-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Iodopyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.