Description

2-Bromo-5-Iodopyridin-4-Amine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an exceptionally valuable intermediate for constructing complex heterocyclic scaffolds. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Cross-Coupling Reactions: An ideal substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo leaving groups.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	2-Bromo-5-Iodopyridin-4-Amine
CAS No.	1300750-78-0
Molecular Formula	C5H4BrIN2
Molecular Weight	298.91 g/mol
Synonyms	4-Amino-2-bromo-5-iodopyridine; 5-Iodo-2-bromopyridin-4-amine; 2-Bromo-5-iodo-4-pyridinamine; 4-Pyridinamine, 2-bromo-5-iodo-; 2-Bromo-5-iodo-4-aminopyridine; 4-Amino-2-bromo-5-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodopyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.