Description

5-Chlorofuro[2,3-B]Pyridine-2-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused-ring structure, which incorporates both aldehyde and halogen functionalities, enabling its use as a versatile precursor for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated heterocyclic core.
• Material Science Precursor: Serves as a building block for creating specialized organic ligands, dyes, and photoactive materials.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The aldehyde and chloro groups make it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Heterocyclic Library Synthesis: A critical starting material for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	5-Chlorofuro[2,3-B]Pyridine-2-Carbaldehyde
CAS No.	1299607-77-4
Molecular Formula	C8H4ClNO2
Molecular Weight	181.57 g/mol
Synonyms	5-Chlorofuro[2,3-b]pyridine-2-carboxaldehyde; 2-Formyl-5-chlorofuro[2,3-b]pyridine; 5-Chloro-2-furo[2,3-b]pyridinecarboxaldehyde; 1299607-77-4; 5-Chloro-furo[2,3-b]pyridine-2-carbaldehyde; 5-Chlorofuro(2,3-b)pyridine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chlorofuro[2,3-B]Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.