Description

n-(4-Chloro-5-Fluoro-3-Iodopyridin-2-Yl)Pivalamide is a high-value, multi-halogenated pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture, featuring chlorine, fluorine, and iodine substituents, makes it an indispensable building block for constructing complex, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways due to its halogen handles for further functionalization.
• Material Science Research: Acts as a monomer or building block for developing specialty polymers and advanced organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	n-(4-Chloro-5-Fluoro-3-Iodopyridin-2-Yl)Pivalamide
CAS No.	1299607-56-9
Molecular Formula	C11H11ClF I N2O
Molecular Weight	368.57 g/mol
Synonyms	2-Pivalamido-4-chloro-5-fluoro-3-iodopyridine; 4-Chloro-5-fluoro-3-iodo-2-(pivalamido)pyridine; Pivalic acid (4-chloro-5-fluoro-3-iodopyridin-2-yl)amide; N-(4-Chloro-5-fluoro-3-iodo-2-pyridinyl)-2,2-dimethylpropanamide; 1299607-56-9; 4-Chloro-5-fluoro-3-iodopyridine-2-carboxamide, N-tert-butyl-; Tert-butylamide of 4-chloro-5-fluoro-3-iodopyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of n-(4-Chloro-5-Fluoro-3-Iodopyridin-2-Yl)Pivalamide is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full spectroscopic data is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.