Description

2,5-Dichloro-4-Iodo-3-Methoxypyridine is a high-value halogenated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it an essential building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the life sciences and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: Serves as a versatile substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the reactive iodine and chlorine substituents.
• Chemical Biology: Utilized in the synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	2,5-Dichloro-4-Iodo-3-Methoxypyridine
CAS No.	1299607-34-3
Molecular Formula	C6H4Cl2INO
Molecular Weight	304.91 g/mol
Synonyms	4-Iodo-2,5-dichloro-3-methoxypyridine; 3-Methoxy-2,5-dichloro-4-iodopyridine; 2,5-Dichloro-3-methoxy-4-iodopyridine; Pyridine, 2,5-dichloro-4-iodo-3-methoxy-; 1299607-34-3; SCHEMBL21806227; AKOS040759232; ZINC000257830511
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-Iodo-3-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.