Description

tert-Butyl 1-((5-Bromopyridin-3-Yl)Methyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, neurology, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small molecule drugs targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex final Active Pharmaceutical Ingredients.
• Kinase Inhibitor Development: Particularly valuable in the research and synthesis of bromopyridine-containing kinase inhibitors for oncology applications.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	tert-Butyl 1-((5-Bromopyridin-3-Yl)Methyl)Piperidin-4-Ylcarbamate
CAS No.	1296223-53-4
Molecular Formula	C17H26BrN3O2
Molecular Weight	384.31 g/mol
Synonyms	1-BOC-4-[[(5-Bromo-3-pyridinyl)methyl]amino]piperidine; tert-Butyl N-[1-[(5-bromopyridin-3-yl)methyl]piperidin-4-yl]carbamate; 4-[[(5-Bromo-3-pyridinyl)methyl]amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[1-[(5-bromo-3-pyridinyl)methyl]-4-piperidinyl]carbamate; 1296223-53-4; BOC-4-((5-Bromopyridin-3-yl)methylamino)piperidine; 1-N-Boc-4-((5-bromopyridin-3-yl)methylamino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-((5-Bromopyridin-3-Yl)Methyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development under ICH guidelines and can supply material suitable for use in cGMP environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.