Description

Benzene, [[[2,2-Dimethyl-4-(trimethylsilyl)-3-butyn-1-yl]oxy]methyl]- is a specialized organosilicon building block featuring a unique combination of a benzene ring, a silyl-protected alkyne, and an ether linkage. This compound matters as a high-value intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of novel functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing or alkyne-functionalized moieties.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides where its specific structure can contribute to enhanced biological activity or environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions due to the presence of the trimethylsilyl-protected alkyne group.
• Ligand and Catalyst Development: Utilized for synthesizing novel ligands or organometallic complexes for catalytic applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in university and corporate research laboratories.

Basic Information

Product Name	Benzene, [[[2,2-Dimethyl-4-(trimethylsilyl)-3-butyn-1-yl]oxy]methyl]-
CAS No.	1294504-65-6
Molecular Formula	C17H26OSi
Molecular Weight	274.48 g/mol
Synonyms	[[(2,2-Dimethyl-4-trimethylsilylbut-3-yn-1-yl)oxy]methyl]benzene; 1-[[(2,2-Dimethyl-4-trimethylsilyl-3-butyn-1-yl)oxy]methyl]benzene; (2,2-Dimethyl-4-trimethylsilylbut-3-ynyloxymethyl)benzene; Benzyl (2,2-dimethyl-4-trimethylsilylbut-3-ynyl) ether; TMS-Protected Alkyne Benzyl Ether Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to a quality management system to support our commitment to supplying high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.