Description

(2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythro-Pentonic Acid-γ-Lactone 3,5-Bis(4-Chlorobenzoate) is a high-purity fluorinated sugar derivative and protected lactone intermediate of significant interest in advanced organic synthesis. Its value lies in its role as a key chiral building block for the development of novel pharmaceuticals and bioactive compounds, particularly those targeting metabolic pathways. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require sophisticated, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated nucleoside analogs and other potential antiviral or anticancer agents.
• Agrochemical Research: Used in the development of new, more selective herbicides and pesticides that leverage fluorinated sugar chemistry.
• Glycobiology & Glycomics: Acts as a specialized probe or building block for studying carbohydrate-protein interactions and enzyme mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and metabolic properties of lead compounds.
• Process Chemistry Development: Used for scaling up synthetic routes to fluorinated target molecules under GMP or non-GMP conditions.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring novel synthetic methodologies involving fluorinated carbohydrates.

Basic Information

Item	Details
Product Name	(2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythro-Pentonic Acid-γ-Lactone 3,5-Bis(4-Chlorobenzoate)
CAS No.	1294481-80-3
Molecular Formula	C20H15Cl2FO6
Molecular Weight	441.24 g/mol
Synonyms	(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythro-pentonic acid γ-lactone 3,5-bis(4-chlorobenzoate); 2-Deoxy-2-fluoro-2-methyl-D-erythro-pentono-1,4-lactone 3,5-di(4-chlorobenzoate); 3,5-Bis(4-chlorobenzoyloxy)-2-deoxy-2-fluoro-2-methyl-D-erythro-pentono-1,4-lactone; Fluorinated Methyl Pentonolactone Bis(4-chlorobenzoate); Protected 2-Fluoro-2-methylpentonolactone derivative; 1294481-80-3
EINECS	Contact for details

Quality Control

Our (2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythro-Pentonic Acid-γ-Lactone 3,5-Bis(4-Chlorobenzoate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.