Description

3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Ol is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its unique molecular scaffold, which combines a chlorinated, trifluoromethyl-substituted bipyridine core with a tetrahydro and hydroxyl functionality, making it a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides, leveraging the bioactivity of the chlorinated trifluoromethylpyridine moiety.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
• Material Science Research: Investigated as a potential ligand or functional component in the development of specialty chemicals and advanced materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Ol
CAS No.	1292498-24-8
Molecular Formula	C12H12ClF3N2O
Molecular Weight	292.69 g/mol
Synonyms	3'-Chloro-5'-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-ol; 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-3-ol; 3-Hydroxy-3-[3-chloro-5-(trifluoromethyl)-2-pyridyl]piperidine; 3-(3-Chloro-5-trifluoromethyl-2-pyridyl)-3-hydroxypiperidine; 3-Piperidinol, 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1292498-24-8; 3'-Chloro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-ol
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.