Description

(S)-2-(3-(Methoxycarbonyl)Pyrrolidin-1-Yl)Acetic Acid is a high-purity chiral intermediate featuring a pyrrolidine scaffold with a carboxylic acid and a methyl ester functional group. This compound matters for its critical role in the synthesis of complex, biologically active molecules, particularly in the development of new pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry for creating novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Research: Used to construct constrained peptide analogs and protease inhibitors due to its pyrrolidine ring structure.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and metal-catalyzed reactions.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and biological pathways.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of target molecules under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(S)-2-(3-(Methoxycarbonyl)Pyrrolidin-1-Yl)Acetic Acid
CAS No.	1292324-46-9
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	1-[(Carboxymethyl)-L-proline methyl ester; (S)-1-(Carboxymethyl)-3-(methoxycarbonyl)pyrrolidine; (S)-2-(3-(Methoxycarbonyl)-1-pyrrolidinyl)acetic acid; Methyl (S)-1-(carboxymethyl)pyrrolidine-3-carboxylate; L-Proline, 1-(carboxymethyl)-, methyl ester; (S)-1-Carboxymethyl-3-methoxycarbonyl-pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-2-(3-(Methoxycarbonyl)Pyrrolidin-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.