Description

2-(n-Boc-n-Butylamino)-5-Bromopyridine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine core protected by a tert-butoxycarbonyl (Boc) group. This compound is critically important for its role in facilitating complex multi-step organic syntheses, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological disorders and cancers.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides.
• Functional Material Development: Employed in creating organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The bromine moiety makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Academic & Contract Research: Essential for medicinal chemistry programs and process optimization studies in R&D laboratories.

Basic Information

Product Name	2-(n-Boc-n-Butylamino)-5-Bromopyridine
CAS No.	1291487-21-2
Molecular Formula	C14H21BrN2O2
Molecular Weight	329.24 g/mol
Synonyms	5-Bromo-2-[(N-tert-butoxycarbonyl-N-butyl)amino]pyridine; 2-[(N-Boc-N-butyl)amino]-5-bromopyridine; tert-Butyl N-butyl-N-(5-bromopyridin-2-yl)carbamate; 2-(N-Boc-N-butylamino)-5-bromopyridine; 5-Bromo-2-(N-Boc-butylamino)pyridine; 2-Amino-5-bromopyridine N-Boc, N-butyl derivative; Boc-Butylamino-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-(n-Boc-n-Butylamino)-5-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.