Description

n-(4-Fluorophenyl)-3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sulfonamide-based scaffolds. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the optimization of lead compounds in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo studies to investigate biological pathways and enzyme interactions involving sulfonamide pharmacophores.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic molecules for advanced material science and agrochemical research.

Basic Information

Product Name	n-(4-Fluorophenyl)-3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide
CAS No.	1291487-08-5
Molecular Formula	C14H11FN4O2S
Molecular Weight	318.33 g/mol
Synonyms	8-[(4-Fluorophenyl)sulfamoyl]-3-methyl-[1,2,4]triazolo[4,3-a]pyridine; 3-Methyl-N-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-sulfonamide; 1291487-08-5; [1,2,4]Triazolo[4,3-a]pyridine-8-sulfonamide, N-(4-fluorophenyl)-3-methyl-; N-(4-Fluorophenyl)-3-methyl-[1,2,4]triazolo[4,3-a]pyridine-8-sulfonamide
EINECS	Contact for details

Quality Control

Our n-(4-Fluorophenyl)-3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.