Description

n-(3,4-Difluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide CAS NO 1291486-52-6 is a high-purity, advanced pharmaceutical intermediate characterized by its unique triazolopyridine sulfonamide core. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in kinase inhibition. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of targeted, small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific kinases and enzymes.
• Biochemical Research: Used as a reference standard or active probe in pharmacological and biological screening assays.
• Agrochemical Development: Serves as a precursor in the research of new crop protection agents with specific modes of action.
• Material Science Research: Investigated for its potential in creating functional organic materials due to its fused heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for organic methodology development and medicinal chemistry studies.

Basic Information

Product Name	n-(3,4-Difluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide
CAS No.	1291486-52-6
Molecular Formula	C13H8F2N4O2S
Molecular Weight	322.29 g/mol
Synonyms	8-[(3,4-Difluorophenyl)sulfamoyl]-[1,2,4]triazolo[4,3-a]pyridine; 1291486-52-6; N-(3,4-Difluorophenyl)-1,2,4-triazolo[4,3-a]pyridine-8-sulfonamide; 1,2,4-Triazolo[4,3-a]pyridine-8-sulfonamide, N-(3,4-difluorophenyl)-; Difluorophenyl Triazolopyridine Sulfonamide; Triazolopyridine Sulfonamide Derivative
EINECS	Contact for details

Quality Control

Our n-(3,4-Difluorophenyl)-[1,2,4]Triazolo[4,3-A]Pyridine-8-Sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.