Description

3-Bromo-5-(4-(Pyrrolidin-1-Yl)Piperidin-1-Ylsulfonyl)Pyridine is a high-value, advanced pharmaceutical intermediate featuring a unique sulfonyl-linked heterocyclic scaffold. This compound matters for its critical role in modern drug discovery, particularly in the development of kinase inhibitors and other targeted small-molecule therapeutics. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to synthesize novel drug candidates for oncology, neurological disorders, and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel kinase inhibitors and other targeted therapeutic agents.
• Drug Discovery Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its privileged piperidine-pyrrolidine pharmacophore.
• Chemical Biology Probe: Serves as a core structure for developing molecular probes to study enzyme function and cellular signaling pathways.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and new reaction development.

Basic Information

Product Name	3-Bromo-5-(4-(Pyrrolidin-1-Yl)Piperidin-1-Ylsulfonyl)Pyridine
CAS No.	1291411-31-8
Molecular Formula	C14H20BrN3O2S
Molecular Weight	374.30 g/mol
Synonyms	3-Bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonyl]pyridine; 3-Bromo-5-((4-(pyrrolidin-1-yl)piperidin-1-yl)sulfonyl)pyridine; 1291411-31-8; 3-Bromo-5-(4-pyrrolidin-1-ylpiperidine-1-sulfonyl)pyridine; Pyridine, 3-bromo-5-[(4-pyrrolidin-1-yl-1-piperidinyl)sulfonyl]-; 3-Bromo-5-(4-(pyrrolidin-1-yl)piperidine-1-sulfonyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(4-(Pyrrolidin-1-Yl)Piperidin-1-Ylsulfonyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.