Description

1-(5-Bromopyridin-3-Ylsulfonyl)-4-Cyclopropylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine and sulfonylpiperazine functional groups. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in kinase inhibitor programs.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Employed in the development of tool compounds for target validation and pathway analysis.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)-4-Cyclopropylpiperazine
CAS No.	1291410-97-3
Molecular Formula	C12H16BrN3O2S
Molecular Weight	346.25 g/mol
Synonyms	4-Cyclopropyl-1-(5-bromopyridin-3-ylsulfonyl)piperazine; 1-[(5-Bromo-3-pyridinyl)sulfonyl]-4-cyclopropylpiperazine; 4-Cyclopropyl-1-(5-bromopyridine-3-sulfonyl)piperazine; 5-Bromo-3-[(4-cyclopropylpiperazin-1-yl)sulfonyl]pyridine; 1291410-97-3; 1-(5-Bromo-3-pyridylsulfonyl)-4-cyclopropylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)-4-Cyclopropylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in regulated environments, including pre-clinical and clinical-stage pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.