Description

1-Oxa-8-Azaspiro[4.5]Decane-3-Methanol is a versatile spirocyclic heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused ring structure containing both oxygen and nitrogen atoms makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require complex, bioactive heterocyclic cores.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chelating ligands and organocatalysts due to its spirocyclic and heteroatom-rich framework.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	1-Oxa-8-Azaspiro[4.5]Decane-3-Methanol
CAS No.	1290625-37-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	3-(Hydroxymethyl)-1-oxa-8-azaspiro[4.5]decane; 1-Oxa-8-azaspiro[4.5]decane-3-methanol; 8-Aza-1-oxaspiro[4.5]decane-3-methanol; Spiro[4.5]decane-3-methanol, 1-oxa-8-aza-; Oxa-azaspirodecane methanol derivative
EINECS	Contact for details

Quality Control

Our 1-Oxa-8-Azaspiro[4.5]Decane-3-Methanol is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.