Description

L-Phenylalanine,n-[(1,1-Dimethylethoxy)Carbonyl]-3-(Methylsulfonyl)-, Phenylmethyl Ester is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of complex peptides and pharmaceutical intermediates, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce modified phenylalanine residues with enhanced stability or specific functional properties.
• Proteomics Research: Employed in the design and synthesis of specialized peptides for biochemical assays, enzyme studies, and protein-protein interaction research.
• Chemical Biology: Serves as a building block for creating labeled peptides, activity-based probes, and other tools for studying biological pathways.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex organic molecules requiring protected amino acid motifs.
• Agrochemical Development: Potential application in the research and development of novel, bioactive compounds for crop protection.

Basic Information

Product Name	L-Phenylalanine,n-[(1,1-Dimethylethoxy)Carbonyl]-3-(Methylsulfonyl)-, Phenylmethyl Ester
CAS No.	1289646-78-1
Molecular Formula	C22H27NO6S
Molecular Weight	433.52 g/mol
Synonyms	Boc-Phe(3-SO2Me)-OBzl; (S)-Benzyl 3-(methylsulfonyl)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate; N-Boc-3-(Methylsulfonyl)-L-phenylalanine benzyl ester; Boc-L-Phe(3-SO2Me)-OBzl; tert-Butyl ((S)-1-(benzyloxy)-3-(methylsulfonyl)-1-oxo-3-phenylpropan-2-yl)carbamate; Fmoc-Phe(3-SO2Me)-OH benzyl ester precursor; Protected 3-(Methylsulfonyl)-L-phenylalanine derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.