Description

(6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine CAS NO 1289387-50-3 is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core and a cyclopropylamine moiety. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, potent drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the construction of targeted kinase inhibitors due to the bromopyridine group's role in forming key molecular interactions.
• CNS Drug Candidates: Employed in the research and development of novel therapeutics for neurological and psychiatric disorders.
• Chemical Biology Probes: Acts as a starting material for creating chemical probes to study biological pathways and protein functions.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) performing bespoke synthesis for clients.

Basic Information

Product Name	(6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine
CAS No.	1289387-50-3
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	Cyclopropyl-(6-bromopyridin-3-ylmethyl)amine; 1-(6-Bromopyridin-3-yl)-N-cyclopropylmethanamine; 3-Pyridinemethanamine, 6-bromo-N-cyclopropyl-; (6-Bromo-3-pyridinyl)methyl]cyclopropylamine; N-[(6-Bromopyridin-3-yl)methyl]cyclopropanamine; (6-Bromo-pyridin-3-ylmethyl)-cyclopropyl-amine
EINECS	Contact for details

Quality Control

Our (6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.