Description

1-(2-Chloro-6-Fluoro-Benzyl)-Azetidine-3-Carboxylic Acid 2-Chloro-6-Fluoro-Benzyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique azetidine carboxylic acid ester structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by fine chemical manufacturers for bespoke synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	1-(2-Chloro-6-Fluoro-Benzyl)-Azetidine-3-Carboxylic Acid 2-Chloro-6-Fluoro-Benzyl Ester
CAS No.	1289385-42-7
Molecular Formula	C18H16ClFNO2
Molecular Weight	323.78 g/mol
Synonyms	1-[(2-Chloro-6-fluorophenyl)methyl]azetidine-3-carboxylic acid 2-chloro-6-fluorobenzyl ester; 2-Chloro-6-fluorobenzyl 1-[(2-chloro-6-fluorophenyl)methyl]azetidine-3-carboxylate; Azetidine-3-carboxylic acid, 1-[(2-chloro-6-fluorophenyl)methyl]-, (2-chloro-6-fluorophenyl)methyl ester; 1289385-42-7; 1-(2-Chloro-6-fluoro-benzyl)-azetidine-3-carboxylic acid 2-chloro-6-fluoro-benzyl ester
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-6-Fluoro-Benzyl)-Azetidine-3-Carboxylic Acid 2-Chloro-6-Fluoro-Benzyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply under more controlled quality agreements as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.