Description

4-(4-Cyano-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional chemical intermediate designed for advanced synthetic applications. This compound is critical for research and development in pharmaceutical chemistry, serving as a versatile building block for creating complex molecular architectures. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides, leveraging its piperidine and pyridine motifs.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used in biochemical and cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(4-Cyano-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1289385-11-0
Molecular Formula	C18H23N3O3
Molecular Weight	329.40 g/mol
Synonyms	1-Boc-4-[(4-cyano-2-pyridyloxy)methyl]piperidine; tert-Butyl 4-[(4-cyano-2-pyridinyloxy)methyl]-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-[(4-cyano-2-pyridyloxy)methyl]piperidine; 4-[(4-Cyano-2-pyridinyloxy)methyl]piperidine-1-carboxylic acid tert-butyl ester; Boc-4-((4-cyano-2-pyridyloxy)methyl)piperidine; N-Boc-4-((4-cyano-2-pyridyloxy)methyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Cyano-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.