Description

tert-Butyl 4-bromopicolinate is a high-purity brominated picolinate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a protected carboxylic acid functionality and a reactive bromine handle, enabling efficient, multi-step synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific picolinic acid derivatives.
• Academic and R&D Laboratories: Used in methodological development and exploratory chemistry for novel heterocyclic compounds.

Basic Information

Product Name	tert-Butyl 4-Bromopicolinate
CAS No.	1289210-83-8
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	4-Bromopicolinic acid tert-butyl ester; tert-Butyl 4-bromo-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 4-bromo-, 1,1-dimethylethyl ester; 4-Bromo-picolinic acid tert-butyl ester; t-Butyl 4-bromopicolinate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-bromopicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥97.0% (by HPLC)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.