Description

Methyl 2-Chloro-4-Cyanonicotinate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials. Its unique substitution pattern offers versatile reactivity for constructing sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active nitrogen heterocycles.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or precursor for functional polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	Methyl 2-Chloro-4-Cyanonicotinate
CAS No.	1289188-60-8
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	2-Chloro-4-cyano-pyridine-3-carboxylic acid methyl ester; Methyl 2-chloro-4-cyano-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 2-chloro-4-cyano-, methyl ester; 2-Chloro-4-cyanonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-4-Cyanonicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your regulatory and research needs, whether for development, pilot-scale, or commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.