Description

4-Bromo-3-Fluoropyridine-2-Carbaldehyde is a high-purity, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents adjacent to an aldehyde group, makes it a versatile precursor for constructing complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridine motifs.
• Ligand & Catalyst Development: Serves as a precursor for creating novel bidentate and tridentate ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and photoactive compounds.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Bromo-3-Fluoropyridine-2-Carbaldehyde
CAS No.	1289148-65-7
Molecular Formula	C6H3BrFNO
Molecular Weight	203.99 g/mol
Synonyms	2-Formyl-4-bromo-3-fluoropyridine; 3-Fluoro-4-bromopyridine-2-carboxaldehyde; 4-Bromo-3-fluoro-2-pyridinecarboxaldehyde; 4-Bromo-3-fluoropicolinaldehyde; 2-Pyridinecarboxaldehyde, 4-bromo-3-fluoro-; 4-Bromo-3-fluoro-2-formylpyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoropyridine-2-Carbaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.