Description

4-Bromo-2-Isobutoxypyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, where the bromine atom serves as an excellent site for cross-coupling reactions, and the isobutoxy group provides steric and electronic modulation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and complex molecular scaffolds. Its precise structure makes it a key intermediate in creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Development: Used in research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine substituent makes it an ideal substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl and C-N bonds.
• Chemical Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fine chemicals.

Basic Information

Product Name	4-Bromo-2-Isobutoxypyridine
CAS No.	1289132-07-5
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	2-Isobutoxy-4-bromopyridine; 4-Bromo-2-(2-methylpropoxy)pyridine; Pyridine, 4-bromo-2-(2-methylpropoxy)-; 4-Bromo-2-isobutyloxypyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Isobutoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.