Description

3-Pyridinecarboxaldehyde, 5-Bromo-4-Fluoro- is a high-purity halogenated pyridine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which enables the construction of complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromo-fluoro substitution pattern can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Scale-up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	3-Pyridinecarboxaldehyde, 5-Bromo-4-Fluoro-
CAS No.	1289120-46-2
Molecular Formula	C6H3BrFNO
Molecular Weight	203.99 g/mol
Synonyms	5-Bromo-4-fluoropyridine-3-carboxaldehyde; 5-Bromo-4-fluoro-3-formylpyridine; 5-Bromo-4-fluoronicotinaldehyde; 3-Formyl-5-bromo-4-fluoropyridine; 5-Bromo-4-fluoro-3-pyridinecarboxaldehyde; 1289120-46-2; 5-Bromo-4-fluoropyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxaldehyde, 5-Bromo-4-Fluoro- is manufactured and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.