Description

5-Bromo-3-Chloro-2-Hydrazinylpyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both halogen substituents and a reactive hydrazine group, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand Synthesis: Serves as a precursor for creating specialized chelating ligands and catalysts used in metal-organic chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis Building Block: Provides a reactive handle for further functionalization, enabling the creation of diverse chemical libraries for screening.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Hydrazinylpyridine
CAS No.	1289076-45-4
Molecular Formula	C5H6BrClN3
Molecular Weight	222.48 g/mol
Synonyms	2-Hydrazinyl-5-bromo-3-chloropyridine; 5-Bromo-3-chloro-2-hydrazinopyridine; 3-Chloro-5-bromo-2-hydrazinylpyridine; 2-Pyridinamine, 5-bromo-3-chloro-2-hydrozinyl-; (5-Bromo-3-chloro-2-pyridinyl)hydrazine; 5-Bromo-3-chloro-pyridine-2-yl-hydrazine; 1289076-45-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloro-2-Hydrazinylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.