Description

4-Chloro-1-Methyl-1H-Pyrazolo[4,3-C]Pyridine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters because it serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific pyrazolopyridine scaffolds for bioactivity.
• Material Science Research: Investigated as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	4-Chloro-1-Methyl-1H-Pyrazolo[4,3-C]Pyridine
CAS No.	1289014-47-6
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	4-Chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine; 1-Methyl-4-chloro-1H-pyrazolo[4,3-c]pyridine; 4-Chloro-1-methylpyrazolo[4,3-c]pyridine; Pyrazolo[4,3-c]pyridine, 4-chloro-1-methyl-; 1289014-47-6; 4-Chloro-1-methyl-1H-pyrazolo[4,3-c]pyridin; 4-Chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine (ACI)
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Methyl-1H-Pyrazolo[4,3-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. For advanced applications, we offer material produced under cGMP guidelines and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.