Description

5-Bromo-2-Isobutoxy-3-Methylpyridine is a high-purity, synthetically valuable halogenated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides, leveraging its halogen and ether functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs and sensors.
• Custom Synthesis and Contract Manufacturing: A crucial starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental research reagent in universities and corporate labs for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-2-Isobutoxy-3-Methylpyridine
CAS No.	1288992-15-3
Molecular Formula	C11H16BrNO
Molecular Weight	258.16 g/mol
Synonyms	5-Bromo-3-methyl-2-(2-methylpropoxy)pyridine; 2-Isobutoxy-5-bromo-3-methylpyridine; 3-Methyl-5-bromo-2-isobutoxypyridine; Pyridine, 5-bromo-2-(2-methylpropoxy)-3-methyl-; 1288992-15-3; 5-Bromo-2-isobutoxy-3-picoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Isobutoxy-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.